BioengineeringbioRxivPreprint
In Vivo Production of a Protein via the Delivery of Plasmid DNA by Computationally Designed Polymer Nanoparticles (PNP)
John D. Fisher, Shannon R. Petersen, Olivia Heynes…·Shashi K. Murthy
This paper demonstrates the design of polymer nanoparticles (PNPs) for in vivo delivery of plasmid DNA encoding a broadly neutralizing anti-HIV antibody, achieving durable protein expression levels.
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