Cryo-EM structure of influenza polymerase bound to the cRNA promoter provides insights into the mechanism of virus replication
Ye Wu, Minke Li, Huanhuan Li, Tianli Sun, Yifan Bai, Shaohui Huang, Yingfang Liu, Huanhuan Liang
This study presents a cryo-EM structure of H5N1 influenza polymerase bound to the cRNA promoter, revealing structural features essential for internal initiation of viral RNA synthesis.
bioRxiv · Sep 23, 2025 · PreprintMicrobiology