Structure-Function Relationship of the Ryanodine Receptor Cluster Network in Sinoatrial Node Cells
Alexander V. Maltsev, Valeria Ventura Subirachs, Oliver Monfredi, Magdalena Juhaszova, Pooja Ajay Warrier, Shardul Rakshit, Syevda Tagirova, Anna Maltsev, Michael D. Stern, Edward G. Lakatta, Victor A. Maltsev
This study examines the structure-function relationship of Ryanodine Receptor (RyR) clusters in sinoatrial node cells, showing how heterogeneities in cluster size and location influence calcium release and action potential firing rates.
Cells · Nov 14, 2024Peer-reviewedBiophysics