A widespread SCCmec-located gene cluster protects methicillin-resistant Staphylococcus aureus against toxic polysulfides
Verena Wiemann, Jan-Samuel Puls, Tomohisa Sebastian Tanabe, Jan-Martin Daniel, Sharmila Sekar, Simon Heilbronner, Tanja Schneider, Christiane Dahl, Fabian Grein, Thomas Fließwasser
This paper identifies a SCCmec-located gene cluster (cst2) that enables MRSA to tolerate polysulfides, giving it a competitive advantage in polysulfide-rich environments.
bioRxiv · Jan 28, 2026 · PreprintMicrobiology