A genetically encoded biosensor reveals heterogenous cAMP dynamics coordinating growth and resuscitation in Mycobacterium tuberculosis
Shaun Wachter, Srivathsa Shankar Kurpad, Amit Singh, Neeraj Dhar
This paper develops a genetically encoded biosensor, rmgCarvi, to monitor cAMP dynamics in Mycobacterium tuberculosis at single-cell resolution, revealing how cAMP levels coordinate growth and resuscitation in response to nutrient availability and host environments.
bioRxiv · Jun 3, 2026 · PreprintMicrobiology