Insights into Intestinal Barrier Disruption During Long-Term Gut Chlamydia Colonization in Mice: A Single-Cell Transcriptomic Approach
Ziqing Wan, Yicun Jiang, Sheng Xie, Jiao Wan, Youyou Huang, Luying Wang, Qi Zhang, Zengzi Zhou, Xin Sun, Chuqiang Shu, Tianyuan Zhang, Qi Tian
This study uses single-cell RNA sequencing to investigate how Chlamydia persists in the gut of mice, revealing disruptions in epithelial tight junctions and immune-cell interactions.
Frontiers in Cellular and Infection Microbiology · Jul 25, 2025Peer-reviewedMicrobiology