This study identifies Collaborative Cross mouse strains susceptible to chlamydial induction of hydrosalpinx, revealing strain-specific differences in infection and pathology outcomes.

Infection and Immunity · Feb 17, 2026Peer-reviewedMicrobiology

Impact of oral Chlamydia Vaccination on Host Gut Microbiome and Metabolites Composition

Youyou Huang, Jiao Wan, Chuqiang Shu, Xichun Yan, Jingyue Ma, Tian Zhang, Jiarong He, Ziqing Wan, Guang Li, Qi Zhang, Zengzi Zhou, Xin Sun, Jing Zhao, Pu Zhang, Luying Wang, , Qi Tian

This study examines the effects of oral Chlamydia vaccination on gut microbiome and metabolite composition, identifying microbial and metabolic changes and potential biomarkers of immunization.

mSystems · Nov 10, 2025Peer-reviewedMicrobiology

Insights into Intestinal Barrier Disruption During Long-Term Gut Chlamydia Colonization in Mice: A Single-Cell Transcriptomic Approach

Ziqing Wan, Yicun Jiang, Sheng Xie, Jiao Wan, Youyou Huang, Luying Wang, Qi Zhang, Zengzi Zhou, Xin Sun, Chuqiang Shu, Tianyuan Zhang, Qi Tian

This study uses single-cell RNA sequencing to investigate how Chlamydia persists in the gut of mice, revealing disruptions in epithelial tight junctions and immune-cell interactions.

Frontiers in Cellular and Infection Microbiology · Jul 25, 2025Peer-reviewedMicrobiology

Comparative Analysis of Phytochemical Constituents of Ginkgo Biloba Flowers and Leaves, and Evaluation of Their Biological Activities

Yuying Wang, Ruihong Li, Xin Sun, Ziming Xia, Guang-Jie Zhang, Bin Li, Ying Tian, Min Li, Shu‐Chen Liu

This study compares the chemical and nutritional composition of Ginkgo biloba flowers and leaves, finding flowers richer in bioactive compounds and showing superior anti-radiation and anti-ferroptosis activity.

Fitoterapia · Jun 15, 2025Peer-reviewedBiochemistry