Population-based structure modeling reveals key roles of nuclear microenvironment in gene functions
Aslı Yıldırım, Nan Hua, Lorenzo Boninsegna, Guido Polles, Ke Qin Gong, Shengli Hao, Wenyuan Li, Xianghong Jasmine Zhou, Frank Alber
The paper uses population-based modeling of Hi-C data to analyze the nuclear microenvironment's role in gene function, revealing structural variability and functional heterogeneity.
bioRxiv · Jul 11, 2021 · PreprintGenomics