Differential activity and expression of human 5β-reductase (AKR1D1) splice variants
Nathan Appanna, Hylton Gibson, Elena Gangitano, Niall J. Dempster, Karen Morris, Sherly George, Anastasia Arvaniti, Laura Gathercole, Brian George Keevil, T.M. Penning, Karl‐Heinz Storbeck, Jeremy Tomlinson, Nikolaos Nikolaou
This study examines the differential expression and activity of three AKR1D1 splice variants in human tissues and cells, showing that AKR1D1-002 is the main functional variant involved in steroid hormone metabolism.
Journal of Molecular Endocrinology · Jan 27, 2021Peer-reviewedMolecular Biology