Fold-change detection of NF-κB at target genes with different transcript outputs
Victor C. Wong, Shibin Mathew, Ramesh Ramji, Suzanne Gaudet, Kathryn Miller‐Jensen
The paper investigates fold-change detection of NF-κB at low and high abundance target genes in single cells and finds that transcriptional noise and promoter-bound NF-κB levels differ from model predictions.
Biophysical Journal · Jan 12, 2019Peer-reviewedSystems Biology