Author

Suzanne Gaudet

Harvard UniversityORCID 0000-0002-5701-2825Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:database / resource· 1 Research Focus:gene regulatory network inference· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

Kathryn Miller‐JenseniD· 2 shared Victor C. WongiD· 2 shared Aaron D. Richardson· 1 shared Adriana San‐MigueliD· 1 shared Alexander O. Tejeda· 1 shared Alice DesbuleuxiD· 1 shared Amélie Dricot· 1 shared Andrew MacWilliams· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersSystems Biology

Kathryn Miller‐JensenORCID

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3 papers

Recent·Most cited

TNF stimulation primarily modulates transcriptional burst size of NF-κB-regulated genes

Victor L. Bass, Victor C. Wong, M. Elise Bullock, Suzanne Gaudet, Kathryn Miller‐Jensen

The paper investigates how TNF stimulation affects transcriptional noise in NF-κB-regulated genes, finding that it primarily increases burst size rather than frequency.

Molecular Systems Biology · Jul 1, 2021Peer-reviewedSystems Biology

A reference map of the human protein interactome

Katja Luck, Dae‐Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana M. Cafarelli, Francisco Jose Campos-Laborie, Benoît Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven J. Deimling, Alice Desbuleux, , Michael A. Calderwood

The paper presents HuRI, a comprehensive human protein-protein interaction map, and demonstrates its utility in understanding cellular function and disease mechanisms.

bioRxiv · Apr 19, 2019 · PreprintSystems Biology

Fold-change detection of NF-κB at target genes with different transcript outputs

Victor C. Wong, Shibin Mathew, Ramesh Ramji, Suzanne Gaudet, Kathryn Miller‐Jensen

The paper investigates fold-change detection of NF-κB at low and high abundance target genes in single cells and finds that transcriptional noise and promoter-bound NF-κB levels differ from model predictions.

Biophysical Journal · Jan 12, 2019Peer-reviewedSystems Biology