Patterned illumination enables denser deep-learning based single-molecule localization microscopy
Jelmer P. Cnossen, Shih-Te Hung, Daniel Fan, Josiah B. Passmore, Lukas C. Kapitein, Nynke H. Dekker, Carlas Smith
This paper introduces SIMCODE, a method combining modulation patterns and deep learning to enhance single-molecule localization microscopy, achieving better resolution and performance in high-density samples.
bioRxiv · Mar 9, 2025 · PreprintBiophysics