Jelmer P. Cnossen

This paper introduces a multimodal platform combining magnetic tweezers and TIRF for high-throughput single-molecule analysis, enabling real-time, parallel measurements of force, torque, fluorescence, and temperature.

This paper introduces SIMCODE, a method combining modulation patterns and deep learning to enhance single-molecule localization microscopy, achieving better resolution and performance in high-density samples.

This paper introduces a spline-based method for depth-dependent PSF calibration in localization microscopy, improving PSF accuracy and localization precision.

The paper improves single molecule localization precision using patterned illumination in a conventional setup, achieving near twofold better precision than standard methods on DNA-origami structures.