Single-cell transcriptomic profiling reveals a novel signature of necrotizing granulomatous lesions in the lungs of Mycobacterium tuberculosis-infected C3HeB/FeJ mice
Shintaro Seto, Shiho Ohmori, Hajime Nakamura, Minako Hijikata, Naoto Keicho
The paper uses single-cell RNA sequencing to analyze lung granulomas in M. tuberculosis-infected mice, identifying novel macrophage subtypes and markers associated with TB pathogenesis.
Frontiers in Immunology · Aug 6, 2025Peer-reviewedMicrobiology