Hajime Nakamura

Clinical isolates of Mycobacterium avium complex reveal an M. intracellulare-associated IL-17/neutrophilic pulmonary immune program in a murine disease model

The paper investigates immune responses to different Mycobacterium avium complex isolates in mice, finding that M. intracellulare induces a distinct IL-17/neutrophilic immune program compared to M. avium.

Strain-dependent disease progression and necrotizing granuloma formation induced by virulent Mycobacterium avium complex strains in a murine model

This study evaluates strain-dependent disease progression and necrotizing granuloma formation in a murine model of MAC-PD using five clinical MAC strains.

Mafb Deficiency in Myeloid Cells Increases Susceptibility to Mycobacterium tuberculosis Infection in Mice

This study shows that Mafb deficiency in myeloid cells increases susceptibility to Mycobacterium tuberculosis infection in mice by impairing macrophage function and immune cell recruitment.

Single-cell transcriptomic profiling reveals a novel signature of necrotizing granulomatous lesions in the lungs of Mycobacterium tuberculosis-infected C3HeB/FeJ mice

The paper uses single-cell RNA sequencing to analyze lung granulomas in M. tuberculosis-infected mice, identifying novel macrophage subtypes and markers associated with TB pathogenesis.