The molecular consequences of androgen activity in the human breast
Florian Raths, Mehran Karimzadeh, Nathan Ing, Andrew Martinez, Yoona Yang, Ying Qu, Tian-Yu Lee, Brianna Mulligan, Suzanne Devkota, Wayne T. Tilley, Theresa E. Hickey, Bo Wang, Armando E. Giuliano, Shikha Bose, Hani Goodarzi, , Simon Knott
This study investigates the molecular effects of androgen in the human breast using single-cell transcriptome, chromatin, and spatial profiling of transgender men undergoing androgen therapy, revealing changes in gene expression, immune populations, vasculature, and metabolism.
Cell Genomics · Mar 1, 2023Peer-reviewedGenomics