Screening of Stereochemically Defined 2,5-Diketopiperazines Identifies Autophagy Inducers without mTORC1 Suppression
Satoshi Yano, Shotaro Uchida, Shota Karakama, Shin Suzuki, Kuniki Kino, Taichi Hara
This study identifies autophagy-inducing 2,5-diketopiperazines (DKPs) that do not suppress mTORC1, revealing stereochemistry's role in their activity.
bioRxiv · Aug 17, 2026 · PreprintBiochemistry