High Affinity binding of Yeast Nucleolin Nsr1 to Co-transcriptionally Formed G4 DNA Obstructs Replication and Elevates Genome Instability
Shivani S. Singh, Alexandra Berroyer, Minseon Kim, Nayun Kim
This study shows that yeast Nsr1 binds G4 DNA with high affinity, obstructs replication, and increases genome instability, with the RGG domain being essential for this effect.
bioRxiv · Mar 24, 2020 · PreprintGenetics