Author

Shizhuo Mu

Children's Hospital of Philadelphia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioinformatics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Research Focus:dimensionality reduction· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Charlly Kao· 1 shared Hakon H. HakonarsoniD· 1 shared Hui‐Qi QuiD· 1 shared Jiong CheniD· 1 shared Joe ChaniD· 1 shared Joost WagenaariD· 1 shared Kai WangiD· 1 shared Li SheniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioinformatics

Charlly Kao

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Single-Cell Omics for Transcriptome CHaracterization (SCOTCH): isoform-level characterization of gene expression through long-read single-cell RNA sequencing

Zhuoran Xu, Hui‐Qi Qu, Joe Chan, Shizhuo Mu, Charlly Kao, Hakon H. Hakonarson, Kai Wang

SCOTCH improves isoform-level gene expression characterization using long-read single-cell RNA sequencing by refining sub-exon boundaries and reducing false positives.

Nature Communications · May 7, 2026Peer-reviewedBioinformatics

QOT: Efficient Computation of Sample Level Distance Matrix from Single-Cell Omics Data through Quantized Optimal Transport

Zexuan Wang, Qipeng Zhan, Shu Yang, Shizhuo Mu, Jiong Chen, Sumita Garai, Patryk Orzechowski, Joost Wagenaar, Li Shen

This paper introduces QOT, a method for efficiently computing sample-level distance matrices from single-cell omics data, showing improved accuracy and robustness over existing OT-based approaches.

bioRxiv · Feb 6, 2024 · PreprintBioinformatics