Human RAD51 paralogue, SWSAP1, fosters RAD51 filament by regulating the anti-recombinase, FIGNL1 AAA+ ATPase
Kenichiro MATSUZAKI, Shizuka Kondo, Tatsuya Ishikawa, Akira Shinohara
This study identifies SWSAP1 as a regulator of RAD51 filament formation by inhibiting the anti-recombinase FIGNL1, which dismantles RAD51 from ssDNA.
Nature Communications · Mar 29, 2019Peer-reviewedMolecular Biology