Midbrain microglia-integrated organoids as a next-generation tool for chronic morphine withdrawal research: A pilot study
Hyun Yi, Shue Liu, Zane R. Zeier, Keith A. Candiotti, Shuanglin Hao
This study develops microglia-integrated midbrain organoids to model chronic morphine withdrawal, identifying immune responses and mitochondrial changes in microglia.
bioRxiv · Oct 30, 2025 · PreprintNeuroscience