Predicting heterogeneity in clone-specific therapeutic vulnerabilities using single-cell transcriptomic signatures
Chayaporn Suphavilai, Shumei Chia, Ankur Sharma, Lorna Tu, Rafael Peres da Silva, Aanchal Mongia, Ramanuj DasGupta, Niranjan Nagarajan
The paper uses single-cell RNA-seq data to predict drug responses and combinations by analyzing intra-tumor transcriptomic heterogeneity in cancer cell lines.
Genome Medicine · Dec 1, 2021Peer-reviewedBioinformatics