GlioME: A Novel Organoid Model Retaining the Glioma Mi-croenvironment for Personalized Drug Screening and Thera-peutic Evaluation
Chengjun Zheng, Pengli Wang, Delong Zhang, Zheng Fang, Yutong Feng, Jie Chen, Jiahong Chen, Yiwen Fu, Bao Yang, Shuqing Yu, Li Min, Bo Xiao, Cencan Xing, Yang Yang, Jianfeng Wang, , Zhaoshi Bao
This paper introduces GlioME, a patient-derived glioma organoid model that retains the tumor microenvironment, showing high responsiveness to chemotherapy and accurately predicting patient response to vebreltinib.
Bioactive Materials · Jul 15, 2025Peer-reviewedCancer Biology