Author

Shyl Lamba

University of California, Los Angeles

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Biology Disciplines

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Genomics· 1

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

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Alex ChialastriiD· 1 shared Elizabeth E. SchaueriD· 1 shared Saumya SarkariD· 1 shared Siddharth S. DeyiD· 1 shared

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1 paper

Recent·Most cited

GenomicsNature Structural & Molecular BiologyPeer-reviewedApr 26, 2024

Combinatorial quantification of 5mC and 5hmC at individual CpG dyads and the transcriptome in single cells reveals modulators of DNA methylation maintenance fidelity

Alex Chialastri, Saumya Sarkar, Elizabeth E. Schauer…·Siddharth S. Dey

The paper introduces Dyad-seq to quantify 5mC and 5hmC at CpG dyads and combines it with transcriptome data (scDyad&T-seq) to show how DNMT1 fidelity depends on methylation density and histone modifications in mouse cells.

15 citations

mouseDNA methylation

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