Author

Si Lok

Great Ormond Street Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Amy HY Tong· 1 shared Bhooma ThiruvahindrapuramiD· 1 shared Brett TrostiD· 1 shared Christian R. MarshalliD· 1 shared Cornelia E. ThoeniiD· 1 shared Damra CamatiD· 1 shared Gary D. BaderiD· 1 shared Ian D. McGilvrayiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Amy HY Tong

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2 papers

Recent·Most cited

The Revised Diploid Genome Sequence of an Individual Human: An Optimized Assembly Workflow for Scaling of near Telomere-to-Telomere Assemblies

Si Lok, Timothy N. H. Lau, Amy HY Tong, Brett Trost, Miriam S. Reuter, Bhooma Thiruvahindrapuram, Tara Paton, Jeffrey R. MacDonald, Lynette Y. S. Lau, Christian R. Marshall, J. Craig Venter, Stephen W. Scherer

The paper revises a human diploid genome assembly using a scalable workflow with Oxford Nanopore reads, achieving high accuracy and contiguity without ultra-long reads or other technologies.

medRxiv · May 8, 2026 · PreprintGenetic & Genomic Medicine

A Single-Cell Woodchuck Liver Atlas Identifies Healthy and Disease-Related Cellular Programs Conserved in Human

Zoe A. Clarke, Jawairia Atif, Xinle Wang, Lewis Y. Liu, Lawrence Wood, Damra Camat, Sai Chung, Xue‐Zhong Ma, Justin Manuel, Si Lok, Timothy Lau, Cornelia E. Thoeni, Tomasz I. Michalak, Ian D. McGilvray, Gary D. Bader, Sonya A. MacParland

This paper creates a single-cell atlas of the woodchuck liver to identify cellular programs in health and disease, showing similarities with human HBV infection.

bioRxiv · Mar 3, 2025 · PreprintCell Biology