CRISPR perturbations at many coronary artery disease loci impair vascular endothelial cell functions
Florian Wünnemann, Thierry Fotsing Tadjo, Mélissa Beaudoin, Simon Lalonde, Ken Sin Lo, Benjamin P. Kleinstiver, Guillaume Lettre
The paper assesses the impact of CRISPR perturbations on vascular endothelial cell functions at CAD loci, identifying variants that significantly affect endothelial phenotypes.
PLoS Genetics · Mar 16, 2023Peer-reviewedGenomics