Sleep and circadian rhythm disruption alters the lung transcriptome to predispose to viral infection
Lewis Taylor, Felix Von Lendenfeld, Anna Ashton, Harshmeena Sanghani, Simona Di Pretoro, Laura E J Usselmann, Maria Veretennikova, Robert Dallmann, Jane A. McKeating, Sridhar R. Vasudevan, Aarti Jagannath
This study shows that sleep deprivation alters the mouse lung transcriptome, suppressing immune systems and activating SARS-CoV-2 replication genes, increasing viral infection risk.
iScience · Dec 24, 2022Peer-reviewedNeuroscience