Robert Dallmann

This paper develops mannose-functionalized nanoparticles loaded with rifampicin to target macrophage-associated mycobacteria, showing improved efficacy and reduced toxicity in preclinical models.

The paper assesses the relationship between tumour circadian clock function and survival in breast cancer patients using a machine-learning model called TimeTeller, finding a negative association between clock function and survival.

This study classifies cell and brain penetrating peptides using machine learning, identifying key physicochemical features that distinguish brain-penetrating peptides from cell-penetrating peptides and non-BPP controls.

This study shows that the host circadian clock modulates Staphylococcus aureus invasion into epithelial cells via the SraP-GP340 pathway.

This study investigates the immunomodulatory effects of cationic antimicrobial copolymers on LPS-stimulated macrophages, finding anti-inflammatory and antimicrobial properties in specific copolymers.

This study identifies ZFHX3's role in regulating circadian gene expression in the SCN by mapping its genomic binding sites and analyzing transcriptomic changes in ZFHX3 mutants.

TimeTeller estimates circadian clock function from single transcriptomes by modeling the multi-dimensional state of the clock, demonstrating its application across species and data types.

This study investigates how Adenosine Kinase affects sleep timing and homeostatic sleep response through distinct molecular pathways in mice.

This study shows that sleep deprivation alters the mouse lung transcriptome, suppressing immune systems and activating SARS-CoV-2 replication genes, increasing viral infection risk.