Rac1, Rac3 GTPases and TPC2 are required for axonal outgrowth and migration of cortical interneurons.
Zouzana Kounoupa, Simona Tivodar, Κostas Theodorakis, Dimitrios Kyriakis, Myrto Denaxa, Domna Karagogeos
This study shows that Rac1 and Rac3 are essential for cortical interneuron migration and axon growth, with TPC2 contributing to the phenotype by affecting axonogenesis and migration.
Journal of Cell Science · Feb 6, 2023Peer-reviewedNeuroscience