Inhibition of mucin-type O-glycosylation impairs melanogenesis, melanoma growth, and metastatic capacity
Tanya Jain, Abhiraj Rajasekharan, Simran Kumari Gorai, Perumal Nagarajan, Santiswarup Singha, Srinivasa‐Gopalan Sampathkumar
This study shows that inhibiting O-glycosylation in melanoma cells reduces melanin production and immune evasion, slowing tumor growth and metastasis in mice.
bioRxiv · Oct 5, 2026 · PreprintCancer Biology