Author

Sinan Zhu

National University of Singapore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Genetic & Genomic Medicine· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:deconvolution· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Xiaoyu SongiD· 2 shared Adriana SistigiD· 1 shared Arjun BhattacharyaiD· 1 shared Cara L. Smith GueyeiD· 1 shared Joseph H. RothsteiniD· 1 shared Laurel A. HabeliD· 1 shared Laurie R. MargoliesiD· 1 shared Lawrence David GerstleyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Xiaoyu SongORCID

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2 papers

Recent·Most cited

S-MiXcan: Inferring Cell-Type-Level Transcriptome-Wide Associations from Bulk Transcriptomics Using GWAS Summary Statistics

SINAN ZHU, Qiao Fan, Xiaoyu Song

Cell-type-aware TWAS from bulk-trained expression models and GWAS summary statistics reproduces individual-level MiXcan results (r > 0.99) and finds 32 genome-wide significant breast cancer genes.

medRxiv · Mar 24, 2026 · PreprintGenetic & Genomic Medicine✦ In-depth digest

Cell-type aware transcriptome-wide association study of mammographic density phenotypes

Adriana Sistig, Joseph H. Rothstein, Sinan Zhu, S. Taylor Head, Yung-Han Chang, Ninah S. Achacoso, Stacey Alexeeff, Vignesh A. Arasu, Tejomay Gadgil, Lawrence David Gerstley, Laurie R. Margolies, Lori C. Sakoda, Li Shen, Cara L. Smith Gueye, Marvella Villaseñor, , Weiva Sieh

This study performs a cell-type-aware transcriptome-wide association study (TWAS) of mammographic density phenotypes, identifying novel genes and prioritizing known GWAS loci through cell-type-specific gene expression analysis.

medRxiv · Nov 25, 2025 · PreprintGenetic & Genomic Medicine