Genetic & Genomic MedicinemedRxivPreprint
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S-MiXcan: Inferring Cell-Type-Level Transcriptome-Wide Associations from Bulk Transcriptomics Using GWAS Summary Statistics
SINAN ZHU, Qiao Fan, Xiaoyu Song
Cell-type-aware TWAS from bulk-trained expression models and GWAS summary statistics reproduces individual-level MiXcan results (r > 0.99) and finds 32 genome-wide significant breast cancer genes.
DOI 10.64898/2026.03.22.26349035