GenomicsbioRxivPreprint
Improving isoform-level eQTL and integrative genetic analyses of breast cancer risk with long-read RNA transcript assemblies
S. Taylor Head, Aryun Nemani, Yung-Han Chang…·Arjun Bhattacharya
1 citation
Author
Joseph H. Rothstein
The University of Texas MD Anderson Cancer CenterORCID 0000-0002-8618-1660Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2022-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship4 shared papersGenetic & Genomic Medicine
Weiva SiehORCID
Mutual co-authors in cluster
5 papers
Recent·Most cited
- Genetic & Genomic MedicinemedRxivPreprint
Cell-type aware transcriptome-wide association study of mammographic density phenotypes
Adriana Sistig, Joseph H. Rothstein, Sinan Zhu…·Weiva Sieh
This study performs a cell-type-aware transcriptome-wide association study (TWAS) of mammographic density phenotypes, identifying novel genes and prioritizing known GWAS loci through cell-type-specific gene expression analysis.
DOI 10.1101/2025.11.25.25341027 - Genetic & Genomic MedicinemedRxivPreprint
Variants in Vitamin D-related Genes and Prostate Cancer Risk in Black Men
Tracy M. Layne, Joseph H. Rothstein, Xiaoyu Song…·Robert J. Klein
This study examines the association between vitamin D-related gene variants and prostate cancer risk in Black men, finding no significant associations after adjustment but some suggestive results.
DOI 10.1101/2024.06.29.24309698 - GeneticsBioinformaticsPeer-reviewed
Admix-kit: An Integrated Toolkit and Pipeline for Genetic Analyses of Admixed Populations
Kangcheng Hou, Stephanie M. Gogarten, Joohyun Kim…·Minxian Wang
Admix-kit provides tools for genetic analysis of admixed populations, enabling simulation, association testing, and polygenic scoring.
23 citationstop 3% - BioinformaticsbioRxivPreprint
MiXcan: a Framework for Cell-Type-Specific Transcriptome-Wide Association Studies with an Application to Breast Cancer
Xiaoyu Song, Jiayi Ji, Joseph H. Rothstein…·Weiva Sieh
MiXcan performs cell-type-specific transcriptome-wide association studies, identifying more breast cancer susceptibility genes than conventional methods by considering cell-type heterogeneity.
1 citation