Author

Sizhen Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Assay:DNA methylation· 1 Organism:human· 1 Approach:simulation· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Xiaofei ZhaoiD· 2 shared Allison Hu· 1 shared Jingyu GuoiD· 1 shared Xiaoyue WangiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 4 mutual co-author links

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2 shared papersBioinformatics

Xiaofei ZhaoORCID

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2 papers

Recent·Most cited

SafeMut: UMI-aware variant simulator incorporating allele-fraction overdispersion in read editing

Xiaofei Zhao, Jingyu Guo, Sizhen Wang

SafeMut simulates small variants in NGS data with UMI awareness and allele-fraction overdispersion, matching wet-lab technical replicates better than existing tools.

Informatics in Medicine Unlocked · Jan 1, 2023Peer-reviewedBioinformatics

Calling small variants with universality and Bayesian-frequentist hybridism

Xiaofei Zhao, Allison Hu, Sizhen Wang, Xiaoyue Wang

UVC improves small variant calling accuracy across diverse sequencing data and outperforms existing callers in multiple benchmarks.

bioRxiv · Aug 23, 2020 · PreprintBioinformatics