Author

Xiaofei Zhao

Beijing National Research Center for Information Science and TechnologyORCID 0000-0002-1665-2498Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:benchmarking· 3 Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Research Focus:variant calling· 2 Assay:DNA methylation· 1 Organism:human· 1 Approach:simulation· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Sizhen Wang· 2 shared Allison Hu· 1 shared Jean Pierre Both· 1 shared Jianshu ZhaoiD· 1 shared Jingyu GuoiD· 1 shared Konstantinos T. KonstantinidisiD· 1 shared Xiaoyue WangiD· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 7 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioinformatics

Sizhen Wang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BinDash 2.0: New MinHash Scheme Allows Ultra-fast and Accurate Genome Search and Comparisons

Jianshu Zhao, Xiaofei Zhao, Jean Pierre Both, Konstantinos T. Konstantinidis

BinDash 2.0 improves genome comparison speed using new MinHash algorithms and SIMD optimizations, achieving faster and accurate large-scale genomic distance estimation.

bioRxiv · Mar 13, 2024 · PreprintBioinformatics

NeoHeadHunter: an algorithm for the detection, ranking and probabilistic classification of neoepitope candidates

Xiaofei Zhao

NeoHeadHunter detects, ranks, and probabilistically classifies neoepitope candidates, outperforming existing methods in detection, ranking, and probability estimation.

bioRxiv · Oct 25, 2023 · PreprintBioinformatics

SafeMut: UMI-aware variant simulator incorporating allele-fraction overdispersion in read editing

Xiaofei Zhao, Jingyu Guo, Sizhen Wang

SafeMut simulates small variants in NGS data with UMI awareness and allele-fraction overdispersion, matching wet-lab technical replicates better than existing tools.

Informatics in Medicine Unlocked · Jan 1, 2023Peer-reviewedBioinformatics

Calling small variants with universality and Bayesian-frequentist hybridism

Xiaofei Zhao, Allison Hu, Sizhen Wang, Xiaoyue Wang

UVC improves small variant calling accuracy across diverse sequencing data and outperforms existing callers in multiple benchmarks.

bioRxiv · Aug 23, 2020 · PreprintBioinformatics