Author

Jingyu Guo

ORCID 0009-0008-9576-3102Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Andy Protter· 1 shared Anna Halberg· 1 shared Brent Louie· 1 shared Gavin Song· 1 shared Gregory R. Luedtke· 1 shared Jia Yi FongiD· 1 shared Pek Yee Lum· 1 shared Sizhen Wang· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenomics

Andy Protter

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2 papers

Recent·Most cited

BioinformaticsInformatics in Medicine UnlockedPeer-reviewedJan 1, 2023

SafeMut: UMI-aware variant simulator incorporating allele-fraction overdispersion in read editing

Xiaofei Zhao, Jingyu Guo, Sizhen Wang

SafeMut simulates small variants in NGS data with UMI awareness and allele-fraction overdispersion, matching wet-lab technical replicates better than existing tools.

DOI 10.1016/j.imu.2023.101307

whole-genome sequencingsimulation

𝕏 PostBluesky

GenomicsbioRxivPreprintApr 18, 2022

Elucidating host cell response pathways and repurposing therapeutics for SARS-CoV-2 and other coronaviruses using gene expression profiles of chemical and genetic perturbations

Zhewei Shen, Anna Halberg, Jia Yi Fong…·Pek Yee Lum

The paper identifies compounds that can be repurposed for SARS-CoV-2 and other coronaviruses by analyzing gene expression profiles from chemical and genetic perturbations.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky