Decoding the IGF1 Signaling Gene Regulatory Network Behind Alveologenesis from A Mouse Model of Bronchopulmonary Dysplasia
Fan Gao, Changgong Li, SM Smith, Neil Peinado, GoleNaz Adeli Kohbodi, Evelyn Tran, Yong‐Hwee Eddie Loh, Wei Li, Zea Borok, Parviz Minoo
The paper constructs a gene regulatory network (GRN) for alveologenesis in a mouse model of BPD, revealing how IGF1 signaling regulates lung development and identifies potential therapeutic targets.
eLife · Oct 10, 2022Peer-reviewedDevelopmental Biology