Differential receptor crosstalk in DRD1-DRD2 heterodimer upon phasic and tonic dopamine signals
Hyunbin Kim, Min‐Ho Nam, Sohyeon Jeong, Hyowon Lee, Soo‐Jin Oh, Jeong-Jin Kim, Nakwon Choi, Jihye Seong
The paper develops multicolor sensors to directly measure DRD1 and DRD2 receptor crosstalk in a heterodimer and finds differential inhibition of activation by phasic and tonic dopamine levels.
bioRxiv · May 13, 2021 · PreprintNeuroscience