Rapamycin attenuated zinc-induced tau phosphorylation and oxidative stress in animal model: Involvement of dual mTOR/p70S6K and Nrf2/HO-1 pathways
Chencen Lai, Zhuyi Chen, Yuanting Ding, Chen Qian, Songbai Su, Heng Liu, Ruiqing Ni, Zhi Tang
This study shows that rapamycin reduces zinc-induced tau phosphorylation and oxidative stress in rats by inhibiting the mTOR/p70S6K pathway and activating the Nrf2/HO-1 pathway.
Frontiers in Immunology · Feb 7, 2022Peer-reviewedNeuroscience