Systems BiologybioRxivPreprint
Dynamic modelling and analysis of autophagy in the clearance of aggregated α-synuclein in Parkinson's disease
Bojie Yang, Zhuoqin Yang, Heng Liu
This paper develops a mathematical model to analyze the dynamic behavior of autophagy in clearing aggregated α-synuclein, revealing tri-stability and feedback mechanisms relevant to Parkinson's disease progression.
DOI 10.1101/2022.08.26.505373