Detection of Multiple Types of Cancer Driver Mutations Us-ing Targeted RNA Sequencing in NSCLC
Sheng Ju, Zihan Cui, Yuayuan Hong, Xiaoqing Wang, Weina Mu, Zhuolin Xie, Zeng XueXia, Lin Su, Qi Zhang, Xiaofeng Song, Songxia You, Ruixin Chen, Weizhi Chen, Xuchun, Jun Zhao
This paper develops an RNA-based panel to detect multiple cancer driver mutations in NSCLC, showing high specificity and sensitivity for SNVs, fusions, and expression, with improved detection limits compared to DNA-seq.
bioRxiv · Aug 25, 2021 · PreprintMolecular Biology