Toll-like receptor 3 orchestrates a conserved mechanism of heart regeneration
Manuel Fiegl, Bernhard Röhrs, Dominik Hau, Sophia Mair, Philipp Niederwanger, Dominik Regele, Lorenzo Merotto, Sonja Töchterle, Clemens Engler, Michael Graber, Elke Kirchmair, Veronika Niedrist, Lynn Muller, Leo Pölzl, Jakob Hirsch, , Can Gollmann-Tepekoeylue
This study identifies TLR3 as a conserved mediator of cardiac regeneration in zebrafish, showing its role in immune cell recruitment and DNA repair after myocardial injury.
bioRxiv · Apr 12, 2024 · PreprintMolecular Biology