Author
University of Cambridge
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Ping Jing Toong, Soraya Boushaki, Salome Jingchen Zhao…·Serena Nik‐Zainal
This study identifies RER deficiency as a new DNA repair defect in cancer, detectable through mutational signatures and linked to therapeutic vulnerabilities.
Cherif Badja, Soraya Boushaki, Yogesh Kumar…·Serena Nik‐Zainal
This study identifies BCOR mutations in hiPSCs as a culture-adaptive state causing chromatin, transcriptomic, and proteomic changes, and develops a qPCR assay for detection.
Salome Jingchen Zhao, Ching Chiek Koh, Rachel Brough…·Serena Nik‐Zainal
The paper shows HRd is a continuum with functional and mutational heterogeneity, highlighting the need for refined molecular classification for precision interventions.
Cherif Badja, Sophie Momen, Ching Chiek Koh…·Serena Nik‐Zainal
This study investigates neurodegeneration in Xeroderma pigmentosum using stem cell-derived neurons, identifying endoplasmic reticulum stress and UPS dysfunction as key factors and developing an early detection assay.