Soumya Sethi

Stable Synthetic Organelles from Aqueous Two-Phase Systemswith Access to the Cell Translation Machinery

This paper introduces dextran-lipid droplets as stable synthetic compartments that can be taken up by cells and access the translation machinery for mRNA-based protein production.

ATP-Powered Signaling between Synthetic and Living Cells

This paper describes a method to deliver DNA signals from synthetic cells to living cells using ATP-driven reactions, with potential applications in gene therapy and cancer treatment.

Synthetic Aptamer Mechanoreceptors Enable Cell-SpecificForce Sensing and Temporal Control via DNA Circuits

This paper introduces a DNA-based mechanosensing platform using aptamers to enable cell-specific force sensing and temporally controlled mechanoresponses through programmable DNA circuits.

Nuclease-Resistant L-DNA Tension Probes Enable Long-TermForce Mapping of Single Cells and Cell Consortia

This paper introduces L-DNA tension probes that resist nuclease degradation, enabling long-term force mapping of single cells and migrating cell populations.