Signatures of selection in pleiotropic genes involved in insect neuronal and immune systems
Sowmya Senthilkumar, Reese A. Martin, Ann Thomas Tate
The paper examines evolutionary rates and disease associations of pleiotropic neuro-immune genes in Drosophila and finds slower evolution correlates with human neurological disease, though pleiotropy alone is not the strongest predictor.
G3 Genes Genomes Genetics · Aug 12, 2026Peer-reviewedEvolutionary Biology