Reese A. Martin

Signatures of selection in pleiotropic genes involved in insect neuronal and immune systems

The paper examines evolutionary rates and disease associations of pleiotropic neuro-immune genes in Drosophila and finds slower evolution correlates with human neurological disease, though pleiotropy alone is not the strongest predictor.

The evolution of investment in innate-like and diversified T cell receptors across development

The paper constructs an agent-based model to explore how ontogeny and environmental factors influence the investment in innate-like versus diversified T cell receptors across vertebrate species.

Pleiotropy increases with gene age in six model multicellular eukaryotes

The paper examines pleiotropy across gene age in six model organisms and finds that middle-aged and ancient genes are more pleiotropic than young genes.