Morpheus-3D: Structural Diversity-Guided Detection and Localization of Protein Fold Switching
Sreeharsh Kuniyil, Vijay Subramanian, Akanksha Arun, Anand Lakshmanan, Ashok Sekhar, Anand Srivastava
Morpheus-3D detects and localizes fold-switching proteins using sequence-based entropy profiles, outperforming existing methods and revealing widespread structural plasticity across proteomes.
bioRxiv · Aug 21, 2026 · PreprintBiophysics