Author

Akanksha Arun

Institute of Genomics and Integrative Biology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:large language model· 1 Assay:protein structure· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Ajit Kumar· 1 shared Anand LakshmananiD· 1 shared Anand SrivastavaiD· 1 shared Ashok SekhariD· 1 shared Bichitra Kumar BiswaliD· 1 shared Chandrima GainiD· 1 shared Debajyoti DasiD· 1 shared Deepanshi GahlotiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

Ajit Kumar

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

RePurpose: An LLM-Assisted, Source-Traceable Drug Repurposing Tool with Retrospective Validation on Clemastine in Multiple Sclerosis

Nitin Nayagam, Akanksha Arun

Large-language-model-assisted repurposing web tool recovered clemastine for multiple sclerosis remyelination only through mechanism-worded, model-dependent queries; its rankings missed later evidence of harm in progressive disease.

bioRxiv · Oct 16, 2026 · PreprintPharmacology & Toxicology✦ In-depth digest

A novel lipid-triggered allosteric site modulates LC3-LIR receptor binding activity

Deepanshi Gahlot, Jesu Castin E, S C Mathur, Debajyoti Das, Ajit Kumar, Akanksha Arun, Chandrima Gain, Mridul Sharma, Ravi Kant Pal, Niyati Jain, Bichitra Kumar Biswal, Rajat Singh, Lipi Thukral

This study identifies a lipid-triggered allosteric site in LC3 that modulates receptor binding activity through conformational changes upon membrane engagement.

Nature Communications · Aug 28, 2026Peer-reviewedBiophysics

Morpheus-3D: Structural Diversity-Guided Detection and Localization of Protein Fold Switching

Sreeharsh Kuniyil, Vijay Subramanian, Akanksha Arun, Anand Lakshmanan, Ashok Sekhar, Anand Srivastava

Morpheus-3D detects and localizes fold-switching proteins using sequence-based entropy profiles, outperforming existing methods and revealing widespread structural plasticity across proteomes.

bioRxiv · Aug 21, 2026 · PreprintBiophysics