Author

Sreelekshmi Sreekumar

University of Illinois Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Seung‐Hyuk ChungiD· 2 shared Ji Hyun KimiD· 1 shared Jihyun KimiD· 1 shared Muhammad Imran IrfaniD· 1 shared Muhammad IrfaniD· 1 shared Phimon AtsawasuwaniD· 1 shared Stephanie Kim· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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2 shared papersBioengineering

Seung‐Hyuk ChungORCID

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2 papers

Recent·Most cited

CRISPR-Edited DPSCs, Constitutively Expressing BDNF Enhance Dentin Regeneration in Injured Teeth

Ji Hyun Kim, Muhammad Imran Irfan, Sreelekshmi Sreekumar, Phimon Atsawasuwan, Stephanie Kim, Seung‐Hyuk Chung

This study shows CRISPR-edited dental pulp stem cells overexpressing BDNF enhance dentin regeneration in injured teeth through inflammation-driven mechanisms.

eLife · Jul 9, 2025Peer-reviewedBioengineering

RNA sequencing reveals key factors modulating TNFa-stimulated odontoblast-like differentiation of dental pulp stem cells

Muhammad Irfan, Jihyun Kim, Sreelekshmi Sreekumar, Seung‐Hyuk Chung

This study uses RNA-seq to analyze transcriptomic changes in dental pulp stem cells during TNFα-stimulated odontoblast-like differentiation, identifying key genes and pathways involved.

bioRxiv · Jan 9, 2025 · PreprintBioinformatics