Cell-intrinsic platinum response and associated genetic and gene expression signatures in ovarian cancer cell lines and isogenic models
Kristin M. Adams, Jae-Rim Wendt, Josie Wood, Sydney L. Olson, Ryan Moreno, Zhongmou Jin, Srihari Gopalan, Jessica D. Lang
This study profiles 36 ovarian cancer cell lines to identify genetic and gene expression signatures associated with platinum response, revealing cell line sensitivity and resistance to cisplatin and carboplatin.
Cancer Gene Therapy · Jul 19, 2025Peer-reviewedCancer Biology